Link oestrogen in obesity

Obesity continues to increase in the United States and throughout the world. The leptin by fat cells and pancreatic insulin B cells are created in direct proportion of body fat. Obese people have higher levels of these two hormones than lean people. Recent studies show that another hormone, estrogen, also has a similar effect.

When estrogen in the rat hypothalamus receptors have been destroyed, rates consume more food, burning less energy and have become obese. Research suggests a link between estrogen and obesity, particularly dangerous accumulation of abdominal fat linked to cardiovascular, cancer and type 2 diabetes. The summary presented by Deborah j. Clegg, Dr.., Assistant Professor of Psychiatry, Obesity Research Center at the University of Cincinnati Academic Health Center at the 234th National meeting of the American Chemical Society, 20 August 2007. Its findings will help researchers in the development of new hormone replacement therapies.

Mr Clegg Estrogen wanted to determine the effect of reduced brain estrogen levels. She studied the estrogen receptor alpha (ERa) in the hypothalamus, where the brain regulates body temperature, hunger and thirst. She learned that the ventromedial (VNM) nucleus and the arcuate nucleus react of hormones and other signals control energy intake and expenditure. A gene-silencing technique called Mr Clegg authorized RNA interference stop alpha receptor in the female rats VNM. In other parts of the brain estrogen receptors are not affected. Decreased estrogen levels, therefore has as metabolic rate and energy levels. Rats is fast becoming the glucose intolerant. While their caloric intake has not changed, they get an abdominal considerable weight.

Mr Clegg believes that the disabling of the ERa in the region of kernel arched hypothalamus may have the same effect. There are two groups of neurons in the region. A reduced consumption of food and it stimulates. Loss of estrogen in the region can increase appetite and weight.

In humans, the accumulation of abdominal fat men and women increases the risk of cardiovascular disease, diabetes and insulin resistance. Young women are protected against these risks, they continue their weight in their hips and bag. However, with the onset of menopause, body fat is stored in the abdomen, increases the risk of health complications. Identifying critical areas of the brain and scientific estrogen associated with weight gain and energy expenditure, receptors one day will be able to develop hormone replacement therapies to help women to avoid many of the risks associated with the onset of menopause.

Wayne McGregor has trained as a dietitian in the United Kingdom. It also has a degree in physical fitness and extensive experience in the teaching of different people to burn fat and build muscle. Its website provides hundreds of free weight loss articles, sample plans, tools, and tables of the nutritional value of common foods.

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